Protein Info for CCNA_01845 in Caulobacter crescentus NA1000

Annotation: two-component response regulator protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 177 transmembrane" amino acids 78 to 96 (19 residues), see Phobius details PF00072: Response_reg" amino acids 8 to 115 (108 residues), 76.2 bits, see alignment E=2.3e-25 PF02954: HTH_8" amino acids 135 to 173 (39 residues), 44.1 bits, see alignment 1.4e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_1767)

Predicted SEED Role

"Dna binding response regulator PrrA (RegA)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8Y0 at UniProt or InterPro

Protein Sequence (177 amino acids)

>CCNA_01845 two-component response regulator protein (Caulobacter crescentus NA1000)
MAEPKRLILIEDDEKFAATLKRSFERRGYEVAHVSGLEQALETLRTFTPRYAVVDLKLAG
ESGLACVRALAERDPDMLIVVLTGFASIATAVEAIKLGACHYLAKPSNTDDIEAAFLKRE
GDIDAAIGGRATSIKNLEWERIHQTLVETDFNISETARRLGMHRRTLARKLEKRRMS