Protein Info for CCNA_01777 in Caulobacter crescentus NA1000

Annotation: hybrid sensor histidine kinase/receiver domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 transmembrane" amino acids 27 to 44 (18 residues), see Phobius details amino acids 50 to 69 (20 residues), see Phobius details amino acids 81 to 102 (22 residues), see Phobius details amino acids 109 to 127 (19 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details amino acids 161 to 182 (22 residues), see Phobius details PF00512: HisKA" amino acids 203 to 260 (58 residues), 41.6 bits, see alignment 1.5e-14 PF02518: HATPase_c" amino acids 307 to 420 (114 residues), 102.8 bits, see alignment E=2.2e-33 PF00072: Response_reg" amino acids 447 to 558 (112 residues), 96.7 bits, see alignment E=1.4e-31

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_1705)

Predicted SEED Role

"FIG00481593: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C7D7 at UniProt or InterPro

Protein Sequence (560 amino acids)

>CCNA_01777 hybrid sensor histidine kinase/receiver domain protein (Caulobacter crescentus NA1000)
MGTVLRTFWTNLAEDYRPAALSRRKQVPLRLFVIVTLCVAALILKNMPFLFGWSVAYLVV
QICELYALKRFINAADPTDRVWVNLVSDVALATVFGWLALPLWEMGTPAGAAGAMLLLSA
SIFTALMGAEGCMVAFISGAGPHVAYLFITPLLAGGGGDPVLPYFLIGGGLFTLTIAMTF
LWSHRAMKAEREARRAAEAQVAARSALIAMVSHELRTPINAIVNGAGRLDAGSAGLIADA
GRMMRTLLNDLLDLSKIEAGRMGVEMVDHDLRAQVSDAVDFWRGAAEAKGVTLTLTGAER
LPRWVRGDPMRLRQVLNNLISNAVKFTTEGGITVDVRPVASGAAAVEIEVRDTGPGLTEA
QIIRLFDPYEQLGSETARNFGGTGLGLAISRDLARLMGGELAASSAPEGGARFVLRLPTP
AGAEPTIQALAEEQDLVLAPRLDAPRILVVDDHDINRRTLRGILEAFGAVVDVAEDALSA
LAVCEDQRFDAIVMDVRMPGMDGLEATRRLRAAGLNRQTPVVAVTGAVSDDEVAACRDAG
MTACVAKPVSARELYAALFA