Protein Info for CCNA_01759 in Caulobacter crescentus NA1000

Annotation: peptidyl-prolyl cis-trans isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF09312: SurA_N" amino acids 56 to 169 (114 residues), 55.2 bits, see alignment E=1.9e-18 PF13624: SurA_N_3" amino acids 56 to 173 (118 residues), 31.2 bits, see alignment E=4.6e-11 PF13616: Rotamase_3" amino acids 225 to 303 (79 residues), 52.2 bits, see alignment E=2.1e-17 amino acids 334 to 407 (74 residues), 26.7 bits, see alignment E=1.7e-09 PF00639: Rotamase" amino acids 227 to 302 (76 residues), 58.6 bits, see alignment E=2.6e-19 amino acids 325 to 404 (80 residues), 36.9 bits, see alignment E=1.5e-12

Best Hits

KEGG orthology group: K03771, peptidyl-prolyl cis-trans isomerase SurA [EC: 5.2.1.8] (inferred from 100% identity to ccs:CCNA_01759)

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8Y4 at UniProt or InterPro

Protein Sequence (449 amino acids)

>CCNA_01759 peptidyl-prolyl cis-trans isomerase (Caulobacter crescentus NA1000)
MRSARSVTTFAAGAASILALTVASLGAPAMAMQQAAPEGVAQAPSAPAAPQPLSESVAAV
VNDDIISSYDLMQRMRLLMATSGMQPTQENLPQIEQEALRSLIDERLQMQELKRVEKQQK
ITIISTDKEVEEQIGDIAQSNRLQPEQLKQQLVAQGIGLDTWRAQLRAESSWQSWIQGRY
GSRLRIGEDQIKAYQRRLADAAAKPQYQISEVFLDAARVGGMEVAVNGATQLINQMQQGA
PFAAVARQFSGSATAANGGEVGWVSQGEMPTEVDAALEQLRPGQLSRPIQVKDGVYIIYL
RDKRAGSKTAIVDLKQVAAPLAADATEAQIAAATKQLVDLKPKITSCQSLEATAAKVDGL
VAGDLGEAEITDLAPAFQEAANKLEVGQISDPIRTDAGLHLIAVCGKRQGGANAPTHDQI
ENRLRGQQLALIAKRYLRDLRNQATIETR