Protein Info for CCNA_01712 in Caulobacter crescentus NA1000

Annotation: CopY/TcrY family transcriptional repressor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 127 PF03965: Penicillinase_R" amino acids 8 to 121 (114 residues), 127.4 bits, see alignment E=1.7e-41

Best Hits

Swiss-Prot: 41% identical to BLAI_BACLI: Penicillinase repressor (blaI) from Bacillus licheniformis

KEGG orthology group: K07737, putative transcriptional regulator (inferred from 100% identity to ccr:CC_1640)

Predicted SEED Role

"Transcriptional repressor, BlaI/MecI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8M5 at UniProt or InterPro

Protein Sequence (127 amino acids)

>CCNA_01712 CopY/TcrY family transcriptional repressor (Caulobacter crescentus NA1000)
METTSQRISGAESEVMKVLWADSPKPAEEVLAILAKDHGWAEGTVKTLLNRLLKKGAIAA
DKDGRRFLYRPLIGREDYVDSESQGLLDRLFDGRLAPLVSHFSKREKLNPEDVAELRRLL
ERIDDGQ