Protein Info for CCNA_01691 in Caulobacter crescentus NA1000

Annotation: tRNA/rRNA methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 61 to 81 (21 residues), see Phobius details PF13847: Methyltransf_31" amino acids 231 to 366 (136 residues), 28.4 bits, see alignment E=1.3e-10 PF01189: Methyltr_RsmB-F" amino acids 232 to 419 (188 residues), 142.2 bits, see alignment E=1.7e-45

Best Hits

KEGG orthology group: K03500, ribosomal RNA small subunit methyltransferase B [EC: 2.1.1.-] (inferred from 100% identity to ccs:CCNA_01691)

Predicted SEED Role

"Sun protein"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8K3 at UniProt or InterPro

Protein Sequence (425 amino acids)

>CCNA_01691 tRNA/rRNA methyltransferase (Caulobacter crescentus NA1000)
MRDGGRVSAAIEVLTEIEARHFPVKMALKRWGETARYAGSKDRAFVSGLVLDGLRRKRSL
GWMMADSTARGVMLGVLAFVWKWPLERIAEAAAEEHGFGALTDVERERLAAPVPIEGAPA
PVAGDYPDWLEPHLARALGADQAAEMRALSERAPVDLRVNTLKTDVERCAKALALIDAAP
AGVLATAFRIPAPAAADRTPSVEAVPAFSKGWFEVQDLGSQIAAAVAGDVKGKQVLDFCA
GGGGKTLALAAAMGNSGQIFAHDSDARRLADTIRRGQRAGVRNLQIRSPIEATPLKGLEG
KIDVVFVDAPCTGAGTWRRHPDAKWRLSPDQLAKRQIEQDSVLEDAAAFVKAGGRMIYVT
CSLLTEENEDRVAAFLERHPEFTVKPIALDGVTHVTPEGYLRLTPHRAGTDGFFAAVLQR
ASYTP