Protein Info for CCNA_01638 in Caulobacter crescentus NA1000

Annotation: beta-lactamase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF00144: Beta-lactamase" amino acids 49 to 426 (378 residues), 232.5 bits, see alignment E=3.9e-73

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_1567)

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8K6 at UniProt or InterPro

Protein Sequence (462 amino acids)

>CCNA_01638 beta-lactamase family protein (Caulobacter crescentus NA1000)
MRIGRSRRRALSLLAGVFGCAAVAATPALALPKGKPEEGGFSAERLKRLDDHMQTMVDRG
QIAGGVTVLARHGRVVQARAFGRRVLGGDPMPMDAIFRIRSETKPVTGVAMMMLYEQGLW
RLDDPVSLHIPEFANLRVAKGVDETGQPILTPVSRSPTMRELMTHTAGFAYGLANDPSSP
ADQAYYRAEVLQSASLTDLVQKVSGLPMFAEPGQLWRYSVAADIQGYIVEKLSGQSLPVF
MQERIFTPLGMKDTAFYVPEEKQARLAALYDGDPATGQLVPAVEGAWRDVSKPPAAPLGG
GGLVSTAGDFARFAQMILNKGELDGVRILKPETVALMTQNHLPEGFVVTTNGTAGVLAPA
ARPFPFAAGMGYGIDMAVAVDPAASGAPVGPGTVSWGGSAGTWFWIDPANNLFFVGMIQR
LGGVGPGLDAQSRTLVYQALERPPMPPVQVSAKAPVRPTVSR