Protein Info for CCNA_01636 in Caulobacter crescentus NA1000

Annotation: alkaline phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 528 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details PF16655: PhoD_N" amino acids 48 to 144 (97 residues), 108.2 bits, see alignment E=2.4e-35 PF09423: PhoD" amino acids 157 to 496 (340 residues), 376.5 bits, see alignment E=1.3e-116

Best Hits

KEGG orthology group: K01113, alkaline phosphatase D [EC: 3.1.3.1] (inferred from 100% identity to ccs:CCNA_01636)

Predicted SEED Role

"alkaline phosphatase D"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.1

Use Curated BLAST to search for 3.1.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C7W8 at UniProt or InterPro

Protein Sequence (528 amino acids)

>CCNA_01636 alkaline phosphatase (Caulobacter crescentus NA1000)
MSVLDRYALSRRRMLAVFGGAAVSAMAIPLESGKALAQAVFQTYPFQLGVASGDPSSDGF
VIWTRLAPEPLEIGYGMPSAPVAVEWEVGDAPNMRNIVAKGTAIAPPELGHAVHVEVGGL
QPNRDYWYRFTAGRERSLLGRARTTPALGAALERVRFAVAGCQHYEQGYYTAYRRLAEEN
PDFVFCYGDYIYEYRGNRVWNSASGPVENVRQHFGGEIYSLDDYRRRYAQYKMDTDLQAA
HAAAPWFTVWDDHEIDNNWVTDLDQDGVDPKIFNLRRQAAVQAYYENMPLRASSFPTGTS
LQIYRRATYGQLLNLNLLDTRQYRTDQPCGDRFGYCDAVEASRAEVIGQVQEKWLTNGLI
ESKSTWNVLAQQIMMMDLDREPGEGKAVNPDSWAGYRMPRNRLLQTIRDRKVGNVVVLTG
DEHQNYAGDLYLDGAKAEGAPIASEFVVTSISSGGDGVDQRADMARIQAANPILKFNNAQ
RGYALCDVTPKAFVTEFKVLDAITRRDGKLSTRAKWALEAGKTGIVQA