Protein Info for CCNA_01635 in Caulobacter crescentus NA1000

Annotation: DNA repair protein recO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 PF11967: RecO_N" amino acids 1 to 68 (68 residues), 51.3 bits, see alignment E=9.7e-18 TIGR00613: DNA repair protein RecO" amino acids 4 to 193 (190 residues), 91.4 bits, see alignment E=3e-30 PF02565: RecO_C" amino acids 84 to 223 (140 residues), 90 bits, see alignment E=1.5e-29

Best Hits

Swiss-Prot: 100% identical to RECO_CAUVN: DNA repair protein RecO (recO) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K03584, DNA repair protein RecO (recombination protein O) (inferred from 100% identity to ccr:CC_1564)

Predicted SEED Role

"DNA recombination and repair protein RecO" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8GVD0 at UniProt or InterPro

Protein Sequence (243 amino acids)

>CCNA_01635 DNA repair protein recO (Caulobacter crescentus NA1000)
MEWEDEAYVLSARSHGETGAIVELLTEARGKVAAHVAGAASRRMKPFLQPGARVIVRYRA
KVEGQLGSATLEPMGEGPSSLFDDRLALAGLSAAAAVAAAALPEREAHPGAFHALEALIR
VLEIPEIWPAVYVRYEAGLLQELGFGLDLSKCAATGAFDDLVYVSPRTGRAVSREAGKPY
HDKLLPLPPFMLSSQGGLAEGDVKAGLDITGHFLEQFVFGPLNRPLPPARLWLLDRLAEA
DKL