Protein Info for CCNA_01630 in Caulobacter crescentus NA1000

Annotation: ribonuclease III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 TIGR02191: ribonuclease III" amino acids 11 to 227 (217 residues), 234.7 bits, see alignment E=4.4e-74 PF14622: Ribonucleas_3_3" amino acids 21 to 144 (124 residues), 98.2 bits, see alignment E=6.5e-32 PF00636: Ribonuclease_3" amino acids 45 to 135 (91 residues), 64 bits, see alignment E=2.9e-21 PF00035: dsrm" amino acids 162 to 226 (65 residues), 59.5 bits, see alignment E=5.9e-20

Best Hits

Swiss-Prot: 100% identical to RNC_CAUVC: Ribonuclease 3 (rnc) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K03685, ribonuclease III [EC: 3.1.26.3] (inferred from 100% identity to ccr:CC_1560)

MetaCyc: 37% identical to RNase III (Escherichia coli K-12 substr. MG1655)
Ribonuclease III. [EC: 3.1.26.3]

Predicted SEED Role

"Ribonuclease III (EC 3.1.26.3)" in subsystem RNA processing and degradation, bacterial or Two cell division clusters relating to chromosome partitioning (EC 3.1.26.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.26.3

Use Curated BLAST to search for 3.1.26.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8H627 at UniProt or InterPro

Protein Sequence (231 amino acids)

>CCNA_01630 ribonuclease III (Caulobacter crescentus NA1000)
MDRRVAAVGDLERRIGHRFEDRELLERALTHASVGDGAKKVRDNEVLEFIGDRVLGLLAA
EALAQRFPKAKEGELAPRLNALVSRETCARVARKAELGPALRLSASSSKIGGRETDSILA
GATEALMAALYQDGGLEAARKVFLDLWNDEFDRAGEGRPRDPKTALQEWAQGQGRPLPTY
RVLDRTGPDHAPVFTVEVSVTGVDPAIAKGKSRQEAEKAAAKALLEREGAG