Protein Info for CCNA_01626 in Caulobacter crescentus NA1000

Annotation: pyridoxal phosphate biosynthetic protein pdxJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 TIGR00559: pyridoxine 5'-phosphate synthase" amino acids 4 to 244 (241 residues), 263.7 bits, see alignment E=8e-83 PF03740: PdxJ" amino acids 4 to 243 (240 residues), 321.3 bits, see alignment E=1.4e-100

Best Hits

Swiss-Prot: 100% identical to PDXJ_CAUVC: Pyridoxine 5'-phosphate synthase (pdxJ) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K03474, pyridoxine 5-phosphate synthase [EC: 2.6.99.2] (inferred from 100% identity to ccs:CCNA_01626)

MetaCyc: 54% identical to pyridoxine 5'-phosphate synthase (Escherichia coli K-12 substr. MG1655)
Pyridoxine 5'-phosphate synthase. [EC: 2.6.99.2]

Predicted SEED Role

"Pyridoxine 5'-phosphate synthase (EC 2.6.99.2)" in subsystem Pyridoxin (Vitamin B6) Biosynthesis (EC 2.6.99.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8H623 at UniProt or InterPro

Protein Sequence (254 amino acids)

>CCNA_01626 pyridoxal phosphate biosynthetic protein pdxJ (Caulobacter crescentus NA1000)
MSLRLGVNIDHVATIRNARGASYPEPVRAAELALIAGADGITAHLREDRRHISDADIAVL
TDLCHKRGKPLNFEMAVTDEMVGIALNARPHAACLVPERREEVTTEGGLDVIKGQKRIAD
ATARLRTVGARVSLFIEPDPDQIRACVTAGAQVVELHTGAYCDAARAGETARAEAILKRL
KAGAALAHELGLEVHAGHGIDYATVKPVAAIPQIAELNIGHFLIGEAIFVGLPEAIHRMR
ALMEAARVELEVLA