Protein Info for CCNA_01574 in Caulobacter crescentus NA1000

Annotation: arsenic resistance protein arsH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 TIGR02690: arsenical resistance protein ArsH" amino acids 4 to 221 (218 residues), 424.9 bits, see alignment E=2.2e-132 PF03358: FMN_red" amino acids 30 to 173 (144 residues), 115.9 bits, see alignment E=6.2e-38

Best Hits

Swiss-Prot: 75% identical to ARREH_RHIME: NADPH-dependent FMN reductase ArsH (arsH) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K11811, arsenical resistance protein ArsH (inferred from 100% identity to ccr:CC_1506)

MetaCyc: 74% identical to ArsH (Pseudomonas putida KT2440)

Predicted SEED Role

"Arsenic resistance protein ArsH" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6Z4 at UniProt or InterPro

Protein Sequence (244 amino acids)

>CCNA_01574 arsenic resistance protein arsH (Caulobacter crescentus NA1000)
MSEFPALDPNFLAKIDEARLEVDARAAHSPRILLLYGSLRERSFSRLLVEEAARILQALG
CETRIFDPRDLPLPDATGPDHPKVQELRALCQWSEGQVWCSPERHGAITGIIKAQIDWIP
LEIGSVRPTQGKTLAVMQVSGGSQSFNAVNTLRLLGRWMRMITIPNQSSVAMAFREFDDN
DRMLPSSYYDRLVDVMEELVKFTLLTRDRADYLVDRYSERKAQGRIPEHVALAAEAMKHE
TAPR