Protein Info for CCNA_01470 in Caulobacter crescentus NA1000

Annotation: cytochrome cbb3 oxidase, diheme subunit, membrane-bound ccoP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 transmembrane" amino acids 32 to 54 (23 residues), see Phobius details TIGR00782: cytochrome c oxidase, cbb3-type, subunit III" amino acids 7 to 288 (282 residues), 341.7 bits, see alignment E=1.7e-106 PF14715: FixP_N" amino acids 11 to 56 (46 residues), 82.4 bits, see alignment 2.2e-27 PF13442: Cytochrome_CBB3" amino acids 111 to 193 (83 residues), 41.3 bits, see alignment E=2.4e-14 amino acids 205 to 281 (77 residues), 46.4 bits, see alignment E=6.1e-16 PF00034: Cytochrom_C" amino acids 113 to 196 (84 residues), 49.9 bits, see alignment E=1e-16 amino acids 208 to 283 (76 residues), 26.9 bits, see alignment E=1.5e-09

Best Hits

Swiss-Prot: 52% identical to FIXP_BRASO: Cbb3-type cytochrome c oxidase subunit FixP (fixP) from Bradyrhizobium sp. (strain ORS 278)

KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 100% identity to ccs:CCNA_01470)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C806 at UniProt or InterPro

Protein Sequence (288 amino acids)

>CCNA_01470 cytochrome cbb3 oxidase, diheme subunit, membrane-bound ccoP (Caulobacter crescentus NA1000)
MADRKIDDATGVETTGHEWDGIRELDNPLPRWWLWIWYATIAFSIGYWVLMPAWPGLNGY
TKGLLNKSDRAEVGQELKALEAHRGEGAAMLRTASLEQIEKDPKLQAYAQQVGQSVFGDN
CATCHGIGGTGSKGYANLRDDVWLWGGKLEDIQYTITHGIRSGAEGARVSQMPAYGRDEM
LKPEQIDDLTEYVVNLSRRPANAAAVARATPLFEAQCSACHGPQGQGNQQLGAPNLTDAD
WLFGADRASIRGQIYAGNGGVMPAWSGRLSPETIKALTVYIHSNAGGQ