Protein Info for CCNA_01432 in Caulobacter crescentus NA1000
Annotation: 3-oxoacyl-(acyl-carrier-protein) synthase III
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to FABH_CAUVC: 3-oxoacyl-[acyl-carrier-protein] synthase 3 (fabH) from Caulobacter vibrioides (strain ATCC 19089 / CB15)
KEGG orthology group: K00648, 3-oxoacyl-[acyl-carrier-protein] synthase III [EC: 2.3.1.180] (inferred from 100% identity to ccs:CCNA_01432)Predicted SEED Role
"3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180)" (EC 2.3.1.180)
MetaCyc Pathways
- superpathway of fatty acids biosynthesis (E. coli) (49/53 steps found)
- superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
- superpathway of fatty acid biosynthesis I (E. coli) (14/16 steps found)
- fatty acid biosynthesis initiation (type II) (3/3 steps found)
- superpathway of fatty acid biosynthesis initiation (4/5 steps found)
- streptorubin B biosynthesis (20/34 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.3.1.180
Use Curated BLAST to search for 2.3.1.180
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0H3C7X2 at UniProt or InterPro
Protein Sequence (325 amino acids)
>CCNA_01432 3-oxoacyl-(acyl-carrier-protein) synthase III (Caulobacter crescentus NA1000) MSVVRSVVTGVGAYLPSKVVTNDDLAKFVDTSDEWIVERTGIRQRHQAADDQPVSDLAFE AAKEALAAAGKTAADVDLIIVATTTGDLTFPATATIVQRKLGAPVGVAFDVQAVCSGFVY AMSVADGFVARGHSKCALVIGAEAMTRLMDWSDRGTCVLFGDGAGAIVLEPGEGEGTTDD RGMLGFALRADGTKQDLLYVDGGPSTTGTVGKLRMLGNQVFKHAVVNISEAIHAAAGKAG VAVADVDWFIPHQANQRILQGVAHRCGIDEEKVISTVAIHANTSAASIPLAFAHGIKDGR IKKGDLLLLEAMGGGLTWGACVVRL