Protein Info for CCNA_01395 in Caulobacter crescentus NA1000

Annotation: electron transfer flavoprotein-ubiquinone oxidoreductase FzeA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 558 PF00890: FAD_binding_2" amino acids 13 to 56 (44 residues), 20.7 bits, see alignment 9e-08 PF13450: NAD_binding_8" amino acids 16 to 61 (46 residues), 27.1 bits, see alignment 1.7e-09 PF21162: ETFQO_UQ-bd" amino acids 215 to 308 (94 residues), 146.2 bits, see alignment E=1.5e-46 PF05187: ETF_QO" amino acids 453 to 555 (103 residues), 167.7 bits, see alignment E=2.6e-53

Best Hits

KEGG orthology group: K00311, electron-transferring-flavoprotein dehydrogenase [EC: 1.5.5.1] (inferred from 100% identity to ccr:CC_1334)

Predicted SEED Role

"Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases (EC 1.5.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C7Z9 at UniProt or InterPro

Protein Sequence (558 amino acids)

>CCNA_01395 electron transfer flavoprotein-ubiquinone oxidoreductase FzeA (Caulobacter crescentus NA1000)
MSEDLERESMEYDVVIVGGGPAGLSAAIRLKQMAAKAGTEISVALLEKGSEVGAHILSGA
VIDPKGLAELFPNWKEEGAPLETPVTKDRFKLLGPQGELSLPMFAMPPFMHNHGCYIASL
ANLTRWLAGKAEELGVEIYPGFAASDLVWNDDGSVKGVVVGVVGIAKDGEKKPDYQPGME
LHGKYVFIAEGVRGSLAKQLIAKFKLDEGKSPQKYGIGIKELWQVPPEQHQPGLAEHTTG
WPLDDQTGGGSFMYHFGDNYVAIGYVVHLNYKNPWLSPFDEFQRFKQHPTVRPHLEGGKR
IAYGARAITEGGYQSVPKLTFPGGALIGCSAGFVNVPRIKGSHNAVKTGILAADAAFEAV
QAGRAGDELTAYQTSYDKSWVAKELKIVRNAKPLLGKFGTALGGALGMADMWVNHLTGGA
LGLFGTLKHDKTDAASTGLAKDYKPIVYPKPDGVISFDKLSSVFLSATNHEEDQPAHLRL
KDPSVPIQVNLPKYGEPARLYCPAGVYEVLYNEQGGDPRFQINAQNCVHCKTCDIKDPSQ
NIVWTTPEGGGGPNYPNM