Protein Info for CCNA_01359 in Caulobacter crescentus NA1000

Annotation: myo-inositol catabolism protein IolB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 PF04962: KduI" amino acids 6 to 265 (260 residues), 363.5 bits, see alignment E=3.1e-113 TIGR04378: 5-deoxy-glucuronate isomerase" amino acids 20 to 266 (247 residues), 348.4 bits, see alignment E=1.1e-108

Best Hits

Swiss-Prot: 55% identical to IOLB_GEOKA: 5-deoxy-glucuronate isomerase (iolB) from Geobacillus kaustophilus (strain HTA426)

KEGG orthology group: K03337, 5-deoxy-glucuronate isomerase [EC: 5.3.1.-] (inferred from 100% identity to ccr:CC_1301)

MetaCyc: 51% identical to 5-deoxy-D-glucuronate isomerase (Bacillus subtilis subtilis 168)
RXN-14150 [EC: 5.3.1.30]

Predicted SEED Role

"5-deoxy-glucuronate isomerase (EC 5.3.1.-)" in subsystem Inositol catabolism (EC 5.3.1.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.- or 5.3.1.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C7W4 at UniProt or InterPro

Protein Sequence (269 amino acids)

>CCNA_01359 myo-inositol catabolism protein IolB (Caulobacter crescentus NA1000)
MMSKLLVRPHAPDATGSVLEVTPASAGWTHVGFQVVKLAAGAVFEGGDPDRETCIVVMSG
TAEVSAQGVSFGAIGGRASVFEDKAPGAVYVPAAIAFSVSAVSDVEVALCSAPGQPGGQA
RLIAEHDMPRETRGRGTNTRFVRNILPETAPADGLLVVEVITPGGHWSSYPPHKHDTAAE
GEETALEETYYHRLNPPQGFAFQRVYTDDRSLDETVCVQDGDVVMVPRGYHPVGAPHGYD
LYYLNVMAGPHRKWIFRNDPAHDWIMRQA