Protein Info for CCNA_01337 in Caulobacter crescentus NA1000

Annotation: GMC family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 540 transmembrane" amino acids 245 to 262 (18 residues), see Phobius details PF00732: GMC_oxred_N" amino acids 11 to 301 (291 residues), 163.7 bits, see alignment E=8.8e-52 PF05199: GMC_oxred_C" amino acids 393 to 530 (138 residues), 132.7 bits, see alignment E=2.1e-42

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_01337)

Predicted SEED Role

"Choline dehydrogenase (EC 1.1.99.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.1.99.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.1

Use Curated BLAST to search for 1.1.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C713 at UniProt or InterPro

Protein Sequence (540 amino acids)

>CCNA_01337 GMC family oxidoreductase (Caulobacter crescentus NA1000)
MGDEAIHLGDYDYIVVGAGSAGCLLANRLSADPRRRVLLLEAGGDDNWIWFHVPVGYLFA
IGNPRADWMLETTPQAGLDGRVLAYPRGKVIGGSSAINAMIYMRGQARDYDGWRQRGLAG
WGWPDVLPYFLKHEDHIDPRGEHHRAGGEYRVEHPRVRWDVLDAIRRAGEQAGIAQVDDF
NGGDNAGSSYFQVNQRAGRRWSTATAFLKPVLSRPNLRLVKGVEVERLIIDGKRVRGLRG
RRGGAAVTASVSGELILAAGAIGSPVILQRSGIGRGETLSRAGVAMVHDLPGVGANLQDH
LQIRPVFKVSGVRTLNTDYANLFRRAGMGLDYLLRRSGPLTMAPSQLGMFCRSGPEYESA
NLEFHFQPLSLDRWGEGLHRFGAVTASVCNLRPSSRGAVSLSGPGLEHSPRIDPNYLATE
EDRRVAVESLKWARRIMGQAALAAYAPEAFRPGPEVDGDAALLAAAKALATTIFHPVGTA
AMGADGDPLAVLDARLRVRGVEGLRVIDASAMPTITSGNTNAPTVMIAEKGAAMILEDSR