Protein Info for CCNA_01249 in Caulobacter crescentus NA1000
Annotation: ABC-transporter substrate binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02016, iron complex transport system substrate-binding protein (inferred from 100% identity to ccr:CC_1191)Predicted SEED Role
"Vitamin B12 ABC transporter, B12-binding component BtuF" in subsystem Coenzyme B12 biosynthesis
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0H3C630 at UniProt or InterPro
Protein Sequence (268 amino acids)
>CCNA_01249 ABC-transporter substrate binding protein (Caulobacter crescentus NA1000) MNAAKAFCALAAAMVLVPAGAWAAPRVMSLDSCADQYVLALAPREAIVGLSHRAVAPDSY LRDKAAGLPLRRATFESLVSARPALVVRQWGGDARLTKALQAKGVATVTLDDATDFDGVR ANVRKVAVALDRRPQGEALIAGMDARLKAAAGAGRGRETLYLTPSGYTAGANTLIDAMLR AAGYANATKAAYFAPVSLEQMVMTPPAAVVLGMFDRARAGADRWGPGRHAALRRAVETRA VAELPAAMVGCSAWFAADAALVLARAAR