Protein Info for CCNA_01242 in Caulobacter crescentus NA1000

Annotation: amino acid permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 531 transmembrane" amino acids 31 to 53 (23 residues), see Phobius details amino acids 61 to 81 (21 residues), see Phobius details amino acids 93 to 114 (22 residues), see Phobius details amino acids 120 to 143 (24 residues), see Phobius details amino acids 153 to 175 (23 residues), see Phobius details amino acids 179 to 198 (20 residues), see Phobius details amino acids 207 to 227 (21 residues), see Phobius details amino acids 247 to 268 (22 residues), see Phobius details amino acids 285 to 308 (24 residues), see Phobius details amino acids 348 to 368 (21 residues), see Phobius details amino acids 397 to 416 (20 residues), see Phobius details amino acids 422 to 442 (21 residues), see Phobius details amino acids 454 to 473 (20 residues), see Phobius details amino acids 489 to 511 (23 residues), see Phobius details PF13520: AA_permease_2" amino acids 28 to 494 (467 residues), 195 bits, see alignment E=2.2e-61 PF00324: AA_permease" amino acids 34 to 471 (438 residues), 135.5 bits, see alignment E=2.4e-43

Best Hits

KEGG orthology group: K03294, basic amino acid/polyamine antiporter, APA family (inferred from 100% identity to ccr:CC_1184)

Predicted SEED Role

"Amino acid transporters"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C7N3 at UniProt or InterPro

Protein Sequence (531 amino acids)

>CCNA_01242 amino acid permease (Caulobacter crescentus NA1000)
MAGNRLFLKKSIASIQKEAAHSQLKRTLGPINLMSLGVGAIIGAGIFVLTGQVASANAGP
AIMLSFIVAGIACALAGLCYAELASTMPVSGSAYTYAYGTLGEVFAWIMGWLLVLEYGVA
ASTVAVGWSGYVVSTLHALGINFPMIQVAGADAPMWATPLIQAVAAPGGGTMFAMTGTLN
LVAAIGIAMVSALLVVGVSESANVNNAIVVIKVIVLVTFIAVGAQYINPANWHPFIPEPT
GQPGEFGIGGIFRGAAIIFFAYVGFEAVSTAAAEAKNPSRDVPIGILGALIICTLIYMAV
AAVMTGVVPFRELASPAPIAVAIDRMGLEWADIPYAAAEGGKLNLLSFAIKIGAITGLSS
VMLVLCYGQTRIFYTMARDGLLPKVFAEIHPKFRTPWLGTILLGVVIAIAASFLPISLLG
DLVSLGTAVAFSIVCLSVIYLRIKHPDLPRPFKVPGGIFTAAAGIAACLFLPYQNFQPMI
VHAMNDNPLPLMILGGYAAVGAIIYIAYGYWHSKLAKGIDITEETDPNSPA