Protein Info for CCNA_01159 in Caulobacter crescentus NA1000

Annotation: transporter, major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 transmembrane" amino acids 17 to 37 (21 residues), see Phobius details amino acids 55 to 77 (23 residues), see Phobius details amino acids 83 to 104 (22 residues), see Phobius details amino acids 109 to 132 (24 residues), see Phobius details amino acids 149 to 170 (22 residues), see Phobius details amino acids 190 to 214 (25 residues), see Phobius details amino acids 240 to 264 (25 residues), see Phobius details amino acids 281 to 300 (20 residues), see Phobius details amino acids 306 to 326 (21 residues), see Phobius details amino acids 341 to 372 (32 residues), see Phobius details amino acids 384 to 405 (22 residues), see Phobius details amino acids 413 to 435 (23 residues), see Phobius details PF07690: MFS_1" amino acids 25 to 388 (364 residues), 73 bits, see alignment E=1.1e-24

Best Hits

KEGG orthology group: K02429, MFS transporter, FHS family, L-fucose permease (inferred from 100% identity to ccr:CC_1103)

Predicted SEED Role

"glucose/galactose transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C7F8 at UniProt or InterPro

Protein Sequence (451 amino acids)

>CCNA_01159 transporter, major facilitator superfamily (Caulobacter crescentus NA1000)
MTDAAITKTTAKGGGVKLAIVYVTCLFFIWALVTNLLDPLLKTMKTVFTLTPVEASLTGF
AFFIAYGIMSLPSAAFLSKLGYARSVMVGLGGIVAGCFIAIAAAKLHTFGVFLVGLFVTA
SGVTLLQVAANPLIASMGKPEESSFRLNLSQAFNSLGAACGLWFGANFLLKGEIFEKDAV
ITDAMREQALGFVSNVYLAIGLGLALFILLIFMVRQKITEAAPKTGQLVNPFTALTSKWA
NLGAIGIFLYVGAEVAISLHLLLFLEQSHILDISAEQAGKLTTFYMVFAMIGRFAGSALL
KTIKDYVMLAIVAVGAIALCLVVILTKDMTPSAHAGTVNLLLASAPVTTGLIPAFAALLI
GLFNSIMFPTIFTLTLQRSSAPTSATSGLLCMAIVGGAFLPLAFAKIEEMTGSMAMGFAA
PLLCYVYVLWFALVAKKAPTHEIQEGVAAGH