Protein Info for CCNA_01095 in Caulobacter crescentus NA1000

Annotation: phenylalanyl-tRNA synthetase beta chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 799 TIGR00472: phenylalanine--tRNA ligase, beta subunit" amino acids 1 to 798 (798 residues), 628.3 bits, see alignment E=1.1e-192 PF01588: tRNA_bind" amino acids 46 to 145 (100 residues), 67.7 bits, see alignment E=2e-22 PF03483: B3_4" amino acids 210 to 389 (180 residues), 198.8 bits, see alignment E=1.3e-62 PF03484: B5" amino acids 409 to 472 (64 residues), 64.3 bits, see alignment E=2.5e-21 PF17759: tRNA_synthFbeta" amino acids 486 to 686 (201 residues), 155.9 bits, see alignment E=2.7e-49 PF03147: FDX-ACB" amino acids 711 to 798 (88 residues), 72.2 bits, see alignment E=9.9e-24

Best Hits

Swiss-Prot: 100% identical to SYFB_CAUVC: Phenylalanine--tRNA ligase beta subunit (pheT) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K01890, phenylalanyl-tRNA synthetase beta chain [EC: 6.1.1.20] (inferred from 100% identity to ccs:CCNA_01095)

Predicted SEED Role

"Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20)" (EC 6.1.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.1.1.20

Use Curated BLAST to search for 6.1.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8M4 at UniProt or InterPro

Protein Sequence (799 amino acids)

>CCNA_01095 phenylalanyl-tRNA synthetase beta chain (Caulobacter crescentus NA1000)
MKFTLSWLKDHLETTATVPEIVAAMTMAGLEVEHVIDPATKLAPFTVCKIVEAARHPNAD
RLQVCQVDTVDGRKEIVCGAPNARPGLTTIYAPIGAYVPGLDVTLVEKPVRGVVSNGMLC
SAAELEYASESDGIMELEGSLAVGTPAVDALGLEAVIDFEVTPNRPDWLGVAGIARDLAA
AGVGTLKDLSIAPIAGTYPSPISVTVDGEACPAFAGRYIRGVKNGPSPKWLQDRLTAIGL
RPINALVDVTNLISYDRARPLHVYDAHKLSGTQISTRLGRHGEHGDEHLIALDGKTYELT
PEMCVIADANGERPIGLGGVMGGESTGCSEDTVDVFVESAWFEPIRIAQTGRTTGIASDA
QYRFARTVDTGSLVPGIELATKLILELCGGEPSEVVYVGEVPAAPKGFAFDPDYVGQLSG
LAVTPEKTHQILAALGFDVVLGSPWTVTPPTFRRDVEGKADLVEEVARIAGYGALPSTPL
PEVPRAVGGILTAKQARARAARRALAAAGYAEAVTFSFTNRKTASLFGGGQDVLVLANPI
ASELDCMRPSLLPNLIEAAGRNARQGFADAALFEIGPTFHGDKPADQRTVVSAILAPKAP
RGWDKAAQGDVFTVKADLLALLEELGAPVASLQTAQGSASSWWHPGRSARLQLGPKAVMA
EFGEIHPAVLKALDVAGPVFGFEITLEAIPEPKKKSIKTKPAFSPSALMPLTRDFAFLVE
KAKAAGDLVKAAAGADKALITAARVFDVYEGPGVPDGFKSVAIEVVVQPREATLTDAEIE
ALSAKVVAAAEKAGGKLRS