Protein Info for CCNA_01031 in Caulobacter crescentus NA1000

Annotation: transporter, major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 transmembrane" amino acids 32 to 36 (5 residues), see Phobius details amino acids 56 to 77 (22 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 115 to 134 (20 residues), see Phobius details amino acids 155 to 177 (23 residues), see Phobius details amino acids 189 to 210 (22 residues), see Phobius details amino acids 244 to 263 (20 residues), see Phobius details amino acids 281 to 303 (23 residues), see Phobius details amino acids 312 to 331 (20 residues), see Phobius details amino acids 454 to 477 (24 residues), see Phobius details amino acids 497 to 516 (20 residues), see Phobius details amino acids 522 to 540 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 22 to 224 (203 residues), 97.1 bits, see alignment E=1.2e-31 amino acids 451 to 549 (99 residues), 23.1 bits, see alignment E=3.2e-09 PF07690: MFS_1" amino acids 23 to 333 (311 residues), 102.8 bits, see alignment E=1.9e-33

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_01031)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6B2 at UniProt or InterPro

Protein Sequence (550 amino acids)

>CCNA_01031 transporter, major facilitator superfamily (Caulobacter crescentus NA1000)
MGAKGQAAPAKGRDTMVVGASSLGTVFEWYDFYLYGSLAPIITSHFFSGVNETTGFILAL
LAFAAGFAIRPLGALIFGRLGDLWGRKNTFLITMLLMGVSTFVVGLLPSYAQIGVAAPIA
LVLMRLVQGLALGGEYGGAATYVAEHAPPGKRGFYTSWIQTTATIGLFLSLAVILVARIQ
LGEEAFKAWGWRIPFLVSLLLLGVSLWIRLKLHESPTFERMIAEGKGSKKPLTEAFGNWP
NLKIVLLALVGLTMGQAVVWYTGQFYALFFLEKTLKLDGALANTLVAVALLIGTPFFVIC
GWLSDKIGRKPIIILGCLLAALTYFPIFKAITTYANPALAKAEATAPVVVTADTATCAFQ
FDLIGKAKFNTPCDVAKAYLAKAGVSYSVQAAPAGTPTAVKVGDVTLEGLDSKGATGQAF
ADARKAWEADLGAQLKAAGYPAKADAALVNKPAVIGLLALLVIYVTMVYGPIAAMLVELF
PTRIRYTAMSLPYHIGNGWFGGFLPTTAFAIVAATGDIYSGLWYPVIIAAITAVVGGLFL
KDTRHNRLED