Protein Info for CCNA_01021 in Caulobacter crescentus NA1000

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1037 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details TIGR01782: TonB-dependent receptor" amino acids 42 to 1036 (995 residues), 488.5 bits, see alignment E=2.2e-150 PF07715: Plug" amino acids 62 to 154 (93 residues), 47.4 bits, see alignment E=3.7e-16 PF00593: TonB_dep_Rec" amino acids 475 to 1001 (527 residues), 118.8 bits, see alignment E=8.9e-38 PF14905: OMP_b-brl_3" amino acids 678 to 768 (91 residues), 31.4 bits, see alignment E=1.7e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_01021)

Predicted SEED Role

"N-acetylglucosamine-regulated TonB-dependent outer membrane receptor" in subsystem Chitin and N-acetylglucosamine utilization or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6A4 at UniProt or InterPro

Protein Sequence (1037 amino acids)

>CCNA_01021 TonB-dependent receptor (Caulobacter crescentus NA1000)
MSQEARKSVLKRGLTLALVAGASQLALASGAFAQQAADNTQVEEVVVTGVRGSQLKSVDL
KRKEAAIVDAISAEDIGKLPDVTIADSLQRISGVQIQRNAGEGATVNIRGLAQVITLLNG
EQYLSAGNMGSAQPNLLDVPSQLMNQVLVYKSTNPRNALSGISGTLDLKTRRPFDFKNGF
TVTGAAEAQRGERTKEDDYLLNGVVNWRNDRVGLMLSAAGSKANLGNNSSGVVGLSGNND
WGGSAATNFVSPHGFESFNRVVERKRLGVNASFQADLGEGFTLIAEGFYAKLDEYNRGAG
INISNRWDGGAFGNWTKPTVSQNTGVNSPANGRPWAAVDEYDIDAWWVNSFSVNRTTKSE
SKNYNLELKYDNGGPFTSEVRAIRASGDRLSMNGQAQGDLSNWQYGPNRFTLFRDANDRT
RGPFYPKAICDQYPSAQRSNAVVGSAGGCYLNPNPQGYGQNPQLRYNISGDHPVWSGFDR
PITGGLGAGKSLKDYMANKDSYAIGAFSSEGNNEVSSDMNVFRAEGHYRFDDKFLGFITK
IDAGVRQSDRSVSVEQFHLFSGFYGGVPGAVQANGSAIPAGGCEAQWKAIDVVMSQNQCQ
AGEFVPDPITGKPVFQGYTVNRPTKLTTYNNTIWVDDLGGVTSGIPGFWAIDPRDFDDAE
AFHKKVFGGAIRVTVPGQTYDVTMKEQSAYGAANFEIGNLHGDFGLRVIQTELNVKQNLT
GDTRNYGDTNADAGDSVSKRKYTDWLPSLNAVYDVNDNWKFRFAYAKTMQPLDLGNYGGG
LSIFTADCGAALPNVRCVTGAAASGNPNLDPWRASNFDGAIEYYFGRASMLNISAFQLKI
DSFVTGGTTTGRFPDQDGVIRRTVNVSLPVQGDGGSVKGLEVGAKVAFSDVLPDMGVISN
FGVDSNYTYSPSHESRLDLEGNEIPFFDNSKHQFNLVGWYQDDKLQARVAYNYRTDRLSG
TMGGGGNAVIPIMQKATGYVDVNVSYNVRDNVTVYFNGSNVTGEIEDYYLRFAKGKTQYA
NQNEFEPRYTLGIRARW