Protein Info for CCNA_00929 in Caulobacter crescentus NA1000

Annotation: Riboflavin-specific deaminase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 TIGR00326: riboflavin biosynthesis protein RibD" amino acids 18 to 308 (291 residues), 187.5 bits, see alignment E=2e-59 PF00383: dCMP_cyt_deam_1" amino acids 22 to 111 (90 residues), 50.7 bits, see alignment E=1.4e-17 PF01872: RibD_C" amino acids 170 to 309 (140 residues), 55.7 bits, see alignment E=5.9e-19

Best Hits

KEGG orthology group: K11752, diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC: 1.1.1.193 3.5.4.26] (inferred from 100% identity to ccr:CC_0885)

Predicted SEED Role

"Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)" in subsystem Riboflavin, FMN and FAD metabolism (EC 1.1.1.193, EC 3.5.4.26)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.193 or 3.5.4.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C5Y7 at UniProt or InterPro

Protein Sequence (331 amino acids)

>CCNA_00929 Riboflavin-specific deaminase family protein (Caulobacter crescentus NA1000)
MMIDAILSPARVIQGFSDALAAAEAYAGATAPNPPVGCVVLDAAGETLAVAAHQRAGQAH
AEAAALAACRERGAAARIDTLLVTLEPCNHHGRTPPCVEAILASPARTVWIAVRDPNLAV
AGGGAARLEAAGLEVRFLSDLAHPEASDLVRRARRLIAPFALWAREGRPWLTIKQAINRQ
GDMIPPPGASTFTSETSLTLAHDLRRRADAIITGSGTVLADAPAFTVRRTPDPRPFARRL
AILDRRRRTPGDYIAAAEGRGFRVSLHDALPSLVSELAADGVLEALVECGPTLLASVLET
GLWDEHVVIRQAARAGDADHIERFARTADQA