Protein Info for CCNA_00892 in Caulobacter crescentus NA1000

Annotation: phosphoenolpyruvate-protein phosphotransferase PtsP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 754 PF01590: GAF" amino acids 32 to 160 (129 residues), 69.2 bits, see alignment E=1.3e-22 PF13185: GAF_2" amino acids 35 to 161 (127 residues), 61.7 bits, see alignment E=2.3e-20 PF05524: PEP-utilisers_N" amino acids 188 to 306 (119 residues), 68.9 bits, see alignment E=1.1e-22 TIGR01417: phosphoenolpyruvate-protein phosphotransferase" amino acids 188 to 733 (546 residues), 406.4 bits, see alignment E=8.9e-126 PF00391: PEP-utilizers" amino acids 331 to 403 (73 residues), 63.9 bits, see alignment E=2.3e-21 PF02896: PEP-utilizers_C" amino acids 430 to 719 (290 residues), 303.7 bits, see alignment E=3.2e-94

Best Hits

KEGG orthology group: K08484, phosphotransferase system, enzyme I, PtsP [EC: 2.7.3.9] (inferred from 100% identity to ccr:CC_0849)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.9

Use Curated BLAST to search for 2.7.3.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C823 at UniProt or InterPro

Protein Sequence (754 amino acids)

>CCNA_00892 phosphoenolpyruvate-protein phosphotransferase PtsP (Caulobacter crescentus NA1000)
MAASGIAVRGPRSLLRQIREAMAGAGPAQGKLDVVVRTIAISMVAEVCSIYLRRASGDLE
LFATEGLAREAVHVTRLKPGEGLVGETMRLGRPLNLSDAASHPSFSYRPETGEDPYHAFL
AVPLLRGGRAIGVLVVQNRTERNYDEEEVEDLQIIAMVLAEMVSSSELLGADELKDVELA
PHKPERLKGSRFAEGLAYGVAVLHEQPVAPETLLSDDALAEEARLTYAIEALQTQIDQML
EGQHGLVGASYEVLETYRLFAHDRGWNRSLQEAVRSGLTAEAAVERVRSEHRARLGQARD
PYLRERLHDLEDLNDRLLRHLSGDVHHVRQLPEDAILIARNLGPADLLEYDRTKLKGILL
EEGSAASHAGIVARALDIPCVGRLVGLRDRVNEGDPVVVDAETQEAWLRPRPDVVKALKA
RMEVRAQRKAEFARLRDTPPITKDGSKVTLLMNAGLAVDLDILGETGAEGIGLFRTEFQF
MVAEELPRLEAQTALYEKVLDAANGMPVTFRTLDLGGDKLLPYMELEREDNPALGWRAVR
MGLDRPALLRMQIRALIKAANGRPLRIMFPLVANVDEFRAARSFVDQEVAWALKRGRPAP
ARLDVGAMIEAPSLLWHLDALLPMTDFVSVGTNDLMQYMFAADRGNPRVSDRYDPLSPAA
LRALKTIQQACADTGTQVSVCGEMAGRPLEAFALVALGFDRLSMPPAGIGPVKQMVLSLD
REAARRNVEALLKGSGGSLRGEIETLARKLYVAV