Protein Info for CCNA_00855 in Caulobacter crescentus NA1000

Annotation: rhamnogalacturonan acetylesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00657: Lipase_GDSL" amino acids 30 to 261 (232 residues), 34.2 bits, see alignment E=3e-12 PF13472: Lipase_GDSL_2" amino acids 33 to 183 (151 residues), 50.6 bits, see alignment E=3.3e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_0812)

Predicted SEED Role

"rhamnogalacturonan acetylesterase" in subsystem L-rhamnose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C4S2 at UniProt or InterPro

Protein Sequence (285 amino acids)

>CCNA_00855 rhamnogalacturonan acetylesterase (Caulobacter crescentus NA1000)
MLKPLLIAAALLALPLTAHAQEPIFKASKIVLVGDSTVAVNSGWGGAFCATHVTSNIACV
NLGRGGRSSRTYREEGSWALALKEMSAGGFDQTFVLIQLGHNDQPGRPERSTDLATEFPA
NLRRFVEEARAAGAKPVLVTPLIRRQFKDGQVYDDLAPWAQAIRKLAAETNTPLVDLHAL
SRDAVQAMGPVAAMRLAEIPPPPEVAASAASGTTTGAMFYEPVLPGAVAPPRPPSPPPSP
PGAMGSFKPVFDYTHLGPEGAALFSAMVARALADVAPALRRNLLP