Protein Info for CCNA_00830 in Caulobacter crescentus NA1000

Annotation: beta-galactosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 549 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF02449: Glyco_hydro_42" amino acids 74 to 222 (149 residues), 38.6 bits, see alignment E=1.3e-13 PF18120: DUF5597" amino acids 397 to 535 (139 residues), 137.1 bits, see alignment E=6.5e-44

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_00830)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C5N2 at UniProt or InterPro

Protein Sequence (549 amino acids)

>CCNA_00830 beta-galactosidase (Caulobacter crescentus NA1000)
MEEAMGMSRFATAVGLALALVCGPLASGAHAADAAMPQLVTKDGRHALMVDGAPFLMLAA
QVNNSSAWPSQMAKVWPAIEKVGANTVQVPIAWEQIEPVEGQFDFSYLDLLLEQARERKV
RLVLLWFGTWKNSSPSYAPEWVKLDDKRFPRLIKDDGERSYSMSPLAKSTLDADRKAFVA
LMTHLKAKDAAQKTVIMVQVENETGTYGSVRDFGPAAQKVFNGPAPATLVKAVGAKPGTW
SQAFGKDADEFFHAWHIGRFVDQVAAGGKAVYPLPMYVNAALRDPIKPGDPKTYSAGGPT
DNVIGVWQAAAPSIDLIAPDIYMKESVKYEAVLGHYARPNNALFVAETGNDPAYARYVFS
TLGKQGIGWSPFGMDYTGYGNYPLGAAKVDEALIEVFAANYRLLAPMARELARLSFEGKV
WGGAEPDDRAAQTTTMGDWTVSLRYGKWQFGASDWTWLKDRPPGPQGPEGGGLVAQLSPN
EFLVTGRNVRVEFGRATADGKPMMMARVEEGHFENGQWVFDRLWNGDQTDYGLNFTGGSQ
ILRVKLATY