Protein Info for CCNA_00773 in Caulobacter crescentus NA1000

Annotation: carboxypeptidase S

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 492 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF04389: Peptidase_M28" amino acids 108 to 221 (114 residues), 30 bits, see alignment E=6.3e-11 PF01546: Peptidase_M20" amino acids 123 to 487 (365 residues), 108.9 bits, see alignment E=5.2e-35 PF07687: M20_dimer" amino acids 242 to 387 (146 residues), 50.7 bits, see alignment E=2.3e-17

Best Hits

KEGG orthology group: K13049, carboxypeptidase PM20D1 [EC: 3.4.17.-] (inferred from 100% identity to ccs:CCNA_00773)

Predicted SEED Role

"M20/M25/M40 family peptidase"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.17.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6J6 at UniProt or InterPro

Protein Sequence (492 amino acids)

>CCNA_00773 carboxypeptidase S (Caulobacter crescentus NA1000)
MGIGGKVALTAVGLVLAVSAVVAVRTATFEAPAQADPAAARLAPARPVDVAKAAEHLAEA
IRFQTISHQNRADDQPAEWDKLHAWLQTTYPQAHKAMTREVVAGHGLVYTWTGSNPALAP
IVLMAHQDVVPVTPGSEGQWTHPPFAGVVADGKVWGRGAIDDKGSLVTIFEALESVAAGG
FKPVRTVIIVSGHDEEVRGEGAQAAAALLKSRNIKAQFVLDEGMAVVADHPVTNEPAAII
GVAEKGYATLKVTAPAVGGHSSAPPKDGGGVVTLSKAVQAIHDNPFPMKFQGPGADMLKA
ISPHASPVVKVFAANTWLFSSLLVKVTAKSPAGAAMLHTTIAPTMLKGSPKENVLPQDAT
AWINYRIAPGDSSDKVMAKAKEAVGDLPVELAFEGHRNEPSAVSSTTSDAWKTLAGLAAD
ESQAPVVPGLVTAGTDSRYMGGVSSDVYRFQPLVLTVDGTKVIHGTDEHISLDNVERMVR
FYQRLVETAGSR