Protein Info for CCNA_00758 in Caulobacter crescentus NA1000

Annotation: translation elongation factor P EF-P

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 188 TIGR00038: translation elongation factor P" amino acids 4 to 186 (183 residues), 215.5 bits, see alignment E=2.5e-68 PF08207: EFP_N" amino acids 5 to 61 (57 residues), 56.7 bits, see alignment E=2.8e-19 PF01132: EFP" amino acids 69 to 122 (54 residues), 75.5 bits, see alignment E=3.9e-25 PF09285: Elong-fact-P_C" amino acids 130 to 185 (56 residues), 78.2 bits, see alignment E=4.6e-26

Best Hits

Swiss-Prot: 100% identical to EFP_CAUVC: Elongation factor P (efp) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K02356, elongation factor P (inferred from 100% identity to cse:Cseg_3970)

MetaCyc: 39% identical to protein chain elongation factor EF-P (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Translation elongation factor P" in subsystem Translation elongation factors eukaryotic and archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8H1A0 at UniProt or InterPro

Protein Sequence (188 amino acids)

>CCNA_00758 translation elongation factor P EF-P (Caulobacter crescentus NA1000)
MKVAASSLRKGSVVDMDGKLYVVLSAENIHPGKGTPVTQLNMRRISDGVKVSERYRTTEQ
VERAFVDDRNHTFLYSDGDGYHFMNPESYDQLVATEDVIGDAAPYLQEGMTVILSTHNDV
PIAIDLPRTVVLEIVDTEPSVKGQTASSSYKPAVLSNGVKTTVPPYITAGTKVVILTEDG
SYVERAKD