Protein Info for CCNA_00684 in Caulobacter crescentus NA1000

Annotation: anti-sigma factor, ChrR-family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 27 to 29 (3 residues), see Phobius details TIGR02451: anti-sigma factor, putative, ChrR family" amino acids 6 to 212 (207 residues), 255 bits, see alignment E=3.3e-80 PF12973: Cupin_7" amino acids 125 to 189 (65 residues), 38.9 bits, see alignment E=3.6e-14

Best Hits

Swiss-Prot: 38% identical to CHRR_RHOS4: Anti-sigma-E factor ChrR (chrR) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

KEGG orthology group: K07167, putative transcriptional regulator (inferred from 100% identity to ccs:CCNA_00684)

Predicted SEED Role

"FIG111991: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6C8 at UniProt or InterPro

Protein Sequence (212 amino acids)

>CCNA_00684 anti-sigma factor, ChrR-family (Caulobacter crescentus NA1000)
MSLRRLPSEERLLAYAAGTLSPPEAVVVATHLALRPETRVWSDLGQAVGGGVLEDLEPSA
LDAGALDKTLALLDQPEPQEPTVRLDKTDPTLPAPLRGFELGPWRWLGPGVRVRDVLGPR
DGDCRVILLKIAPGQSTPLHTHGGVELTCVIEGAYATESGVFEEGDFEEADPSVLHQPRV
VSSKPCLCVAALDGQIQLPGRMGKLLAPFVKL