Protein Info for CCNA_00611 in Caulobacter crescentus NA1000

Annotation: beta-lactamase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 490 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF00144: Beta-lactamase" amino acids 38 to 369 (332 residues), 185.4 bits, see alignment E=8.3e-59

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_00611)

Predicted SEED Role

"Beta-lactamase (EC 3.5.2.6)" in subsystem Beta-lactamase or Tn552 (EC 3.5.2.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.6

Use Curated BLAST to search for 3.5.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C672 at UniProt or InterPro

Protein Sequence (490 amino acids)

>CCNA_00611 beta-lactamase (Caulobacter crescentus NA1000)
MMRFSGDGLQRRSFLALVSTTPLLTAWDVRAQTRPDPIDALVAKIVTEHQADGISVAVVQ
DNRTRHYNAGLMARDGSPVSERSVFEIGSISKTFTGLLLAHAIKERRLVASDDVRQHLPA
GYDNLVRDGRPVRLIDLVNTTSALPDNIPDWRTAAANAKPSEAALVAAQMLANYSTDQLM
IDLRNASLVDVPGRTPRHSNVASELLRVVLERVYGQSYQTLLARYIERPFGMGAGVVEPP
RSILARGYDGTGLEAPPSIDAVSLGAGNLRYSAIDMARYLNAHLAASSPAIALTHEPTFG
TPETGAIGYHWLVNKTADSQLYLSHSGSTYGFSSYCEFYPGKGYGSVILANRVGLEWRLG
ELARAVHETLFGPPAGLKALEAMLEESDYADVAASVSLVRQRYPELHLTEDYVNGWGYRL
IEAGRPVAGRAMFAFNVASFPASANAYDSYGDGLAATGDKGAAISNYRRSLELNPGNDHA
REMIAKLVQP