Protein Info for CCNA_00574 in Caulobacter crescentus NA1000

Annotation: alpha-N-acetylglucosaminidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 770 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF12971: NAGLU_N" amino acids 35 to 109 (75 residues), 47.3 bits, see alignment E=2.2e-16 PF05089: NAGLU" amino acids 128 to 491 (364 residues), 414.1 bits, see alignment E=5.7e-128 PF12972: NAGLU_C" amino acids 500 to 759 (260 residues), 184.8 bits, see alignment E=3.8e-58

Best Hits

KEGG orthology group: K01205, alpha-N-acetylglucosaminidase [EC: 3.2.1.50] (inferred from 100% identity to ccs:CCNA_00574)

Predicted SEED Role

"Alpha-N-acetylglucosaminidase (EC 3.2.1.50)" in subsystem Chitin and N-acetylglucosamine utilization (EC 3.2.1.50)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.50

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C518 at UniProt or InterPro

Protein Sequence (770 amino acids)

>CCNA_00574 alpha-N-acetylglucosaminidase (Caulobacter crescentus NA1000)
MPMKASLNRRQAISLAAAAFVASPALAAGSTDGVAAARASLKRLFGRRLAGAHLTVTPGA
ERSWYAIGGKGGAISISGDSPVALVRGAYAHLRQAGLAHVSWEGDRVVQAGAVPAGAGAR
VETPFRHRAYLNTCTYGYTTPWWGWGRWTREIDWMAAHGIDMPLAMEGQEYVWRALWREF
GLSEAELADYFSGPAFTPWHRMGNIEGYKAPLPTAWIDKKKDLQVKILGRMRSLGMTPIL
PAFGGYVPKAFAEKNPKARIYRMRPWEGFHETYWLDPADPLFAKIAARFLALYTETFGAG
TYYLADSFNEMLPPINADGADARDAAYGDGTANTAVTKTKVEVDPALKAQRLAAYGKAIY
DSIRQTRPDAVWVMQGWLFGADSHFWDPAAISAYLSLVPDDKLMILDIGNDRYPNVWKNA
KAFGGKPWIYGYVHNYGGSNPVYGDLGFYRQDIPAIAANPDAGKLAGFGMFPEGLHNNSI
VYEAVYDLAWSEGQASPATWLTRYARARYGKTSPALDAALGQLVEAAFSTRYWSPRWWKS
KAGAYLFFKRPTATVGDFPQHPGDRAKLEAAVKALTALAPTYGQEPLFVLDLTDATRHLA
TMKIDDLLQVAVAAYRRGDTAAGDAARVEIEALALSIDKLLGVQPDTLATWIDEARAYGD
TPADAAAYVANAKAQVTIWGGEGNLNDYASKAWQGLYKSFYLPRWSRFLDALKAAGTGTF
DEVTVTRGGVAWERAWVEAEVAYRREKPADPIGEIKTLIARIDRGGEKTP