Protein Info for CCNA_00573 in Caulobacter crescentus NA1000

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 923 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details TIGR01782: TonB-dependent receptor" amino acids 77 to 923 (847 residues), 619.6 bits, see alignment E=5.4e-190 PF07715: Plug" amino acids 105 to 200 (96 residues), 58.1 bits, see alignment E=1.2e-19 PF00593: TonB_dep_Rec" amino acids 442 to 890 (449 residues), 108.4 bits, see alignment E=8.4e-35

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_0539)

Predicted SEED Role

"N-acetylglucosamine-regulated TonB-dependent outer membrane receptor" in subsystem Chitin and N-acetylglucosamine utilization or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C423 at UniProt or InterPro

Protein Sequence (923 amino acids)

>CCNA_00573 TonB-dependent receptor (Caulobacter crescentus NA1000)
MKKVLEWSASCLQCATSPQSVFAPLSQGGIQKMTNTKTTATAGRRKAFVIALLSGACFAE
AALAQSTPAPAADQAAVDEVVVTAFRKSLATALEVKRKDVRVSDGISSEDIGKFPSENIA
EAIQRIPGVQISAINGRGSTISIRGLGPQYALTTVNGQAFKSSNFTDGFRYDVIQTELAS
GIQVYKSPTADMDAGGLAGTVNIDTVHPFDVKGRQIIVAGKLQQQELIGGNPTGKYGLTY
VDHFLDGKLGVFLGGGYQELKDRGDYLWMDRWTVSNNVYTPARLRYRRIDRETKRSMING
AVQWKPTEHLQMDLIGTYAEDKTTQNIHQQVFLFTTPSASNVVPITVANGTSTKVQVNNF
RLENNQQYENRPQSTSALTTKLHYTGLENWDFNAVAHYSRGNAKHNEEAAVLGINIPSAT
VDIADPKNVIFTTSTALTNTAQYAPTTLIRNTYPTGAFRTVGSHESAAQFDAKRYLDWGI
LESVQVGAKTRSEVLKRYVIRKDNQVVPASFSPTMANSGIAVTNFLDGQMTLPNAWVSPN
LDAYREALKAQGISVYEGFDPLGSYRVERDLTSVYAMANLRGEVLSKSYRANIGVRNEST
DQTIKGYIGSTANPQNTEVRLAAGNYTAKKSYDNLLPSANLSVDLTDNLLLRVAAAKVLV
RPIIDSSNQLARTMTSATDTTGRRIFTISSGQGNLNPMTANQLDLTLEWYYGQGNGLSAG
YFSKKVKNGVFSQLTCPTSYESVALSRDSSGVCVAANGDNYMITESFNDSRVVDIHGYEV
NWQQSLDAWLPIEGFGLIANYTHVTPAKSTTGFRLANLSEHTANGTVYWENQKFSARLSA
NYRSAYDQTSVESFFAGPLGHTIKARTQLDLNLGYNFNERLSFAFAAMNINNAQEEAYLI
NASRWQETAVTGPSYFLSFQYKM