Protein Info for CCNA_00568 in Caulobacter crescentus NA1000

Annotation: N-acetylglucosamine-6-phosphate deacetylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00221: N-acetylglucosamine-6-phosphate deacetylase
  • amino acids 3 to 376 (374 residues), 309.5 bits, E=1.5e-96
• PF01979: Amidohydro_1
  • amino acids 52 to 376 (325 residues), 69.3 bits, E=1.8e-23

Best Hits

KEGG orthology group: K01443, N-acetylglucosamine-6-phosphate deacetylase [EC: 3.5.1.25] (inferred from 100% identity to ccs:CCNA_00568)

Predicted SEED Role

"N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)" in subsystem Chitin and N-acetylglucosamine utilization or Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 3.5.1.25)

MetaCyc Pathways

• N-acetylglucosamine degradation I (2/2 steps found)
• N-acetylglucosamine degradation II (2/3 steps found)
• D-galactosamine and N-acetyl-D-galactosamine degradation (2/4 steps found)
• N-acetyl-D-galactosamine degradation (2/5 steps found)
• peptidoglycan recycling I (8/14 steps found)
• superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation (2/6 steps found)
• chitin derivatives degradation (2/8 steps found)
• superpathway of N-acetylneuraminate degradation (12/22 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Galactose metabolism
• Nucleotide sugars metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.25

Use Curated BLAST to search for 3.5.1.25

Sequence Analysis Tools

See A0A0H3C418 at UniProt or InterPro

Protein Sequence (387 amino acids)

>CCNA_00568 N-acetylglucosamine-6-phosphate deacetylase (Caulobacter crescentus NA1000)
MPIALVNGRVLTPAGFVSGKAVLVENGVVVALLDARDVPADAQRHDLGGDRLVPGFIDTQ
VNGGGGALFNDAPTARTIATIGEAHRAYGTTGFLPTLISDDLEVVDAALRATEDAIAQGV
PGVLGVHIEGPFLNPKRKGIHDEAKFRVIDEDAIALLSSLKRGKLLLTLAPERTTPDIIA
RLAAAGVIVAAGHTNAHYETMRRALDHGLTGVTHLFNAMSPLTSREPGVVGAVLENQNAW
AGIIVDGRHVDPVTLKIALRTRPLDRFMLVTDAMPTVGLTNKRFNLQGREIVVRDGVCVD
EAGTLAGSDLDMAAAVRNAVSMLGLTLEDAVMMASAAPSALLGLQQRRGAIAPGLAADFC
RLDDALNVTSTWIDGKETHARQEALLV