Protein Info for CCNA_00538 in Caulobacter crescentus NA1000

Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 598 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 183 to 205 (23 residues), see Phobius details PF00672: HAMP" amino acids 205 to 254 (50 residues), 33.3 bits, see alignment 5e-12 PF00015: MCPsignal" amino acids 403 to 556 (154 residues), 159.8 bits, see alignment E=6.2e-51

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to ccr:CC_0504)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C5P6 at UniProt or InterPro

Protein Sequence (598 amino acids)

>CCNA_00538 methyl-accepting chemotaxis protein (Caulobacter crescentus NA1000)
MRISGTLNLFAIVLIAAFALATGTATYALMTLRVGGPLSKQQMEVDALVADIMPPPLFIV
EALLTAHRGPDELDMGAEIDRDLTTLHASYEDRHAHWATRPLTPEVKDGLAASDIQVRKF
WDIAEKQFRPALRAGDVAAMNTALDAMTIAYREHRRVITELTPLVVGLSKAKVEAAEAQS
QRIFIAVGLATALMLIVAAGGVWILRRKMVRPLLGMTGYMGALADGNYDKDVPYQGRADE
LGDMARSVGVFRTAVLERRAAREQQLAADARAMDAQQRQAAQSQADARARDLVVSALDRG
LNGLARGELQQRIDEPFPAEFEQLRINFNASVQMLEATLAKVIALAGSVGGGAGEISSAA
DDLSRRTEQQAASLEETAAALQEVTSTIRQSAERAAMAQQATSRSRSSVTQSADLAGEAI
GAMERIDTSSRQINQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAMEVRALAQ
RSADAAKEIKGLIAEASSSVDSGVGLVGRVGQALGAVVDEFSGIEALVNDIATTAKEQAT
GLGQINTAVSQMDQVTQQNAAMVEETTAASHSLKREASDLMNLVRAFSLSEDVRQKAA