Protein Info for CCNA_00444 in Caulobacter crescentus NA1000

Annotation: chemotaxis protein methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 PF03705: CheR_N" amino acids 25 to 77 (53 residues), 62.3 bits, see alignment 2.7e-21 PF01739: CheR" amino acids 92 to 288 (197 residues), 226.9 bits, see alignment E=1.6e-71

Best Hits

Swiss-Prot: 56% identical to CHER_RHIEC: Probable chemotaxis protein methyltransferase (cheRch1) from Rhizobium etli (strain CFN 42 / ATCC 51251)

KEGG orthology group: K00575, chemotaxis protein methyltransferase CheR [EC: 2.1.1.80] (inferred from 100% identity to ccr:CC_0435)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6W0 at UniProt or InterPro

Protein Sequence (293 amino acids)

>CCNA_00444 chemotaxis protein methyltransferase (Caulobacter crescentus NA1000)
MSTVTAPSSDRREAIVDGEFAFTNQDFKRIAALLYDLAGISLPDSKATLVYSRLAKRLRA
LGLRSFNEYCSFVASDKGHDESQEMLRALTTNVTRFFREPHHFDDLRANVLEPVADKVRA
GGRLRLWSAASSSGQEPYSMAFTVLSVWPNAADLDIRILGTDIDTNVLATGRAAVYDESL
LEGIPTAARGQYFERDTSDRRGWRVCEAARSLVAFRELNLNGPSWPMKGPFDAIFCRNVV
IYFDEPTQERVWNRFAPLVAPGGRLYVGHSERVGTSVTAFESCGLTAYRKVGR