Protein Info for CCNA_00439 in Caulobacter crescentus NA1000

Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 673 transmembrane" amino acids 27 to 52 (26 residues), see Phobius details amino acids 207 to 231 (25 residues), see Phobius details PF00672: HAMP" amino acids 232 to 279 (48 residues), 23.5 bits, see alignment 5.7e-09 PF00015: MCPsignal" amino acids 424 to 581 (158 residues), 195.4 bits, see alignment E=7.1e-62

Best Hits

Swiss-Prot: 100% identical to MCPA_CAUVC: Chemoreceptor McpA (mcpA) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to ccs:CCNA_00439)

Predicted SEED Role

"Chemoreceptor mcpA (Methyl-accepting chemotaxis protein)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6V6 at UniProt or InterPro

Protein Sequence (673 amino acids)

>CCNA_00439 methyl-accepting chemotaxis protein (Caulobacter crescentus NA1000)
MLAIRGHGALVGGDLAMKRIRLVDLPLIIKIGFAPAFALLMLAVMAGGAILVQKSQSAAL
KQVVERDMRQNLEIQRISKRISNINGELFVVMTHKAGNIDVDKNDARMAAVLVETDAVKK
DLLALKSKLPAEEQPKIAELIKSLEECRSAIDTVSGMISVDFNMAAGFIAPFEEQYVKMT
GQLDQVVAAANQRIESESAKRQAQATAAMSVTIIMSLLTLGAVGALAFLTVMTTRKSIND
IAAATDKLSKGDNSIDLEKMTRGDELGGIVTALKVFRDNQVHLEQLRADQEKSAALTADE
RRSKEAAAAAAAQEASLVVSNLAEGLEKLASGDLTFRVTADFPGDYRKLKDDFNAAMGSL
QETMKVIAASTDGLSTGADEIAHASDDLSRRTEQQAASLEETAAALDELTATVRRTAAGA
RQASDVVSTTRGEATHSGQVVHQAVSAMGEIEKSSGQISQIIGVIDEIAFQTNLLALNAG
VEAARAGEAGRGFAVVAQEVRALAQRSAEAAKEIKALISSSTQQVSQGVSLVGQTGEALQ
RIVTKVGEIDALVTEIAASAAEQATGLNEVNTAVNQMDQVTQQNAAMVEQSTAATHSLKG
ETAELVRLMARFQVGSGSSSYARPAVADAGHHAPARNPVAEQQARLNTFARPGRSSGSAA
LAQAPASDGWEEF