Protein Info for CCNA_00437 in Caulobacter crescentus NA1000

Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 537 PF11563: Protoglobin" amino acids 9 to 170 (162 residues), 146.5 bits, see alignment E=6.9e-47 PF00015: MCPsignal" amino acids 298 to 453 (156 residues), 182.6 bits, see alignment E=6.1e-58

Best Hits

Swiss-Prot: 35% identical to MCPE_RHIME: Probable chemoreceptor McpE (mcpE) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to ccr:CC_0428)

Predicted SEED Role

"methyl-accepting chemotaxis protein McpB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C5E5 at UniProt or InterPro

Protein Sequence (537 amino acids)

>CCNA_00437 methyl-accepting chemotaxis protein (Caulobacter crescentus NA1000)
MGTAMNQDYAIGERTAFMGIDDKARSALRDLRPVIRAEIGKALDNFYGKVRATPETRKFF
SDDRHMNAASSRQQAHWGVIAEGQFSDDYVQAVRAIGQTHARIGLEPRWYIGGYAVVGDH
LVRAVIDSMWPRGLLAKGGSDRAGEAVAALMKAIFLDMDFAISIYLETLENERQRLEAEQ
KATRARQEHVVTLLAEALDRLAAGDLLARIDGEVCSEFEKLKADFNHAVELLDQAMCGVG
GATEGIRSSTEEISVAADDLSRRTEQQAASLEQTAAALDEITATVRRSAAGAKQAQEVVA
GAKTEAERSGSVVNQAVAAMGEIETSSREIGNIIGVIDEIAFQTNLLALNAGVEAARAGE
AGRGFAVVAQEVRALAQRSADAAKEIKALINTSTKQVEAGVALVGQTGDALRGIVSKVAE
IDELIAQISVSAQEQSGGLHEVNTAVNQMDQVTQQNAAMVEQTTAATHSLKSQTGELVRQ
VETFRTSEGRRSSAAASPAPVQMAQPARSPRPQSRPGGPPISRGATAVAVKEEWEEF