Protein Info for CCNA_00403 in Caulobacter crescentus NA1000

Annotation: short chain dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 323 PF00106: adh_short" amino acids 27 to 232 (206 residues), 90.9 bits, see alignment E=7.8e-30 PF13561: adh_short_C2" amino acids 33 to 242 (210 residues), 62.7 bits, see alignment E=4.1e-21

Best Hits

Swiss-Prot: 45% identical to OXIR_STRAT: Probable oxidoreductase from Streptomyces antibioticus

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_00403)

Predicted SEED Role

"oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6R5 at UniProt or InterPro

Protein Sequence (323 amino acids)

>CCNA_00403 short chain dehydrogenase (Caulobacter crescentus NA1000)
MSGRITSAFGAKSTAREVVAGHDLSGRVAIVTGAATGIGVETARALALAGAEVIIAARKP
ELGEEVANAINEEAGSKRVSFGMLDLSSLEAIRHFVNVWGDRRIDILINNAAVMASPLMR
TADGFEMQFGTNHLGHFLLSVLLAPNLIAGAKASGKPSRLVSLSSIGHRRSGIHFDDPNY
TTRPYEKWEAYGQAKTANSLFAVGFDKRFKDQGVHANAVMPGGILTPLQRHLPIEEQRAL
GWLDENDQPREGFKTTEQGAATSVWAAVGSELEGVGGLYLEDCNQALPWSKENPWTGVMP
HALDPEAADRLWDLSVDIVGAGA