Protein Info for CCNA_00377 in Caulobacter crescentus NA1000

Annotation: chromosome partition protein Smc

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1147 TIGR02168: chromosome segregation protein SMC" amino acids 2 to 1138 (1137 residues), 1012.1 bits, see alignment E=0 PF02463: SMC_N" amino acids 4 to 1131 (1128 residues), 196.6 bits, see alignment E=5.7e-62 PF13476: AAA_23" amino acids 5 to 221 (217 residues), 62.1 bits, see alignment E=1.7e-20 PF13304: AAA_21" amino acids 26 to 98 (73 residues), 31.4 bits, see alignment 3e-11

Best Hits

Swiss-Prot: 100% identical to SMC_CAUVN: Chromosome partition protein Smc (smc) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K03529, chromosome segregation protein (inferred from 100% identity to ccs:CCNA_00377)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8GZ28 at UniProt or InterPro

Protein Sequence (1147 amino acids)

>CCNA_00377 chromosome partition protein Smc (Caulobacter crescentus NA1000)
MQFQRLRLSGFKSFVEPTEFRIEPGLTGIVGPNGCGKSNLLEALRWVMGANSAKAMRAGG
MDDVIFAGSGARPARNHADVTLTIDNADRTAPAQFNDDPILEVVRRIDRGEGSTYRINGR
EVRARDVQLLFADASTGANSPALVRQGQISELIGAKPQNRRRILEEAAGVSGLHTRRHEA
ELRLRAAETNLSRLEDVARELETALNRLRREARQAEKYKRLSSEIRAVQGAVLYARWTEA
RDHLERTTSEATAAARLVEETARASAAAQVAITEAEAAMPPLREEATIAQAILGQLAIQK
DRAEREAEAAAAEFERLSNDLSRIDADRAREAQAKDDAAAALARIAPELEEVRALVAAAP
ERGPELAAVAKAAEEARAAAEAAVEQLAARVAAEEAQGRAAAARLSEAEARANRTNRALE
QARAERAAVGPEVDPAAADARQRFANAEAALAAARAALEEAETARVKAAEQEAQARQLAR
SVEDQLGRLRTEARGLAQLTAPRSKSGHAPALDSVSPDKGYGAALAAALGDDLDAALDPK
APSYWGGAEAPAPVWPEGAEPLAPLVKAPPALAARLSHVAVVTRANGDRLQKELKPGMRL
VSKDGDLWRWDGFVARADAPRPAAVRLEQRTRLAEVEAEIDVMAPRAEATTIALKAAADR
LRAAEDLLRDKRRGPPDAERLLTQAREQVAKFEREQALRAARAQSLDDTIGRFEAEKVEA
DAALGEAREAHAAAQTSGDLQPQLAEARQAAAQAREAAGAARTALDVETRERAGRQRRLE
SLERDRADWSKRAEAAAKRAESLEGDRVKAAAALEAAREAPAALQEKLVALLDEFAAAEA
RRAKASDALETAETTRLNADRAARAAEQAAGEAREKRAALVAHLDGARQRFAEVASAIRE
QARMEPEELGRHVAGEAVAVPKDAAGVEAHLFALERERDAIGPVNLRAEEEAQEYAGRLE
TMRSERADLSGAVTKLRAGIEELNAEGRERLLAAFDVINANFQTLFQALFGGGQAELKLI
ESDDPLEAGLEIFACPPGKRMASMSLMSGGEQALTASALIFGVFLANPAPICVLDEVDAP
LDDANVDRYCNMLDEMRRRTQTRFIAITHNPVTMSRMDRLFGVTMAERGVSQLVSVDLST
AEKLVAA