Protein Info for CCNA_00364 in Caulobacter crescentus NA1000
Annotation: deoxyhypusine synthase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to DHSL_CAUVC: Deoxyhypusine synthase-like protein (CC_0359) from Caulobacter vibrioides (strain ATCC 19089 / CB15)
KEGG orthology group: K00809, deoxyhypusine synthase [EC: 2.5.1.46] (inferred from 100% identity to ccr:CC_0359)Predicted SEED Role
"Deoxyhypusine synthase (EC 2.5.1.46)" (EC 2.5.1.46)
MetaCyc Pathways
- hypusine biosynthesis (4/5 steps found)
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.5.1.46
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0H3C5P8 at UniProt or InterPro
Protein Sequence (364 amino acids)
>CCNA_00364 deoxyhypusine synthase (Caulobacter crescentus NA1000) MFQRRASKVRETEAMNAPVPNNQKAELLQKVVEHVDITSYDARPIIDSMRKMSFSSRDTA RAADIFNMALADKGCSTWLILAGSTSAGGCMHVYRDMVKNGMIDAVVATGASIVDMDFFE ALGFKHYQAAGPVDDNVLRDNYIDRIYDTYIDEEELQACDHTILEICNKLEPRGYSSREF IWEMGKWLAEGNAKKEGSLIQTAYEEGVPIFCPAFVDSSAGFGLVKHQKEKIAEKKPYLM IDAVADFRELTDVKIAAGTTGLFMVGGGVPKNFAQDTVVCAEILGVEADMHKYAIQITVA DVRDGACSSSTLKEAASWGKVSTTYEQMVFAEATTVVPLIASDAYWRKAWEGREKPRWNK LFGK