Protein Info for CCNA_00339 in Caulobacter crescentus NA1000

Annotation: transporter, major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 63 to 85 (23 residues), see Phobius details amino acids 92 to 115 (24 residues), see Phobius details amino acids 122 to 140 (19 residues), see Phobius details amino acids 152 to 175 (24 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 240 to 262 (23 residues), see Phobius details amino acids 277 to 298 (22 residues), see Phobius details amino acids 309 to 329 (21 residues), see Phobius details amino acids 335 to 359 (25 residues), see Phobius details amino acids 371 to 391 (21 residues), see Phobius details amino acids 410 to 428 (19 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 386 (357 residues), 175.8 bits, see alignment E=1.2e-55 PF03137: OATP" amino acids 223 to 329 (107 residues), 33.9 bits, see alignment E=1.2e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_0336)

Predicted SEED Role

"Major facilitator family transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6K2 at UniProt or InterPro

Protein Sequence (438 amino acids)

>CCNA_00339 transporter, major facilitator superfamily (Caulobacter crescentus NA1000)
MRRASMSEDVNKAETAGRGGRYRYVVLAMLILAYTFNFLDRQILGILAGSIKAELHLTDT
QLGLMGGVAFAALYTTLGVPLAWLADRVSRTWIMTVALTVWSGFTVVCGLAGGFWSLFLA
RMGVGVGEAGGVAPAYSLIADYFPKEQRARALAVYSFGIPLGTALGVLFGGLIAAYVDWR
FAFIAVGLAGVAFAPIFKWVVKDPVRGGLDRAPGEVAPAEPPKAPAFGQVLATVMPKPSF
WLLSFGAACSSICGYGVAFWLPTFFQRSFGLSLTDRALYYSALSLFGGVAGIWLGGVLAD
RFGAKNKAAYALAPAICFLVALPCFLLAMNVQSMVVAFLLFLIPTGLNLAWLGPVVAAVQ
HLAPPSMRTTTSALFLLINNLLGLAVGLWFFGYVSDLLTPRYGAESMRYAIYYGLSFYVV
AAVLLILASRRLSKDWAE