Protein Info for CCNA_00311 in Caulobacter crescentus NA1000

Annotation: Zn-dependent protease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 PF01523: PmbA_TldD_1st" amino acids 21 to 85 (65 residues), 45 bits, see alignment E=1.5e-15 PF19290: PmbA_TldD_2nd" amino acids 127 to 219 (93 residues), 44 bits, see alignment E=4.3e-15 PF19289: PmbA_TldD_3rd" amino acids 227 to 442 (216 residues), 236.6 bits, see alignment E=2.9e-74

Best Hits

KEGG orthology group: K03592, PmbA protein (inferred from 100% identity to ccs:CCNA_00311)

Predicted SEED Role

"TldE protein, part of TldE/TldD proteolytic complex"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C495 at UniProt or InterPro

Protein Sequence (443 amino acids)

>CCNA_00311 Zn-dependent protease family protein (Caulobacter crescentus NA1000)
MDDNLLHDVVAAARKAGADAAEAVFAERQSLSVSVRLGELEEVEREEARDLGLRVFIGQR
SATVSGSDISSEARAKLVERAVAMARLAPEDPYASLAPQDRLAHGPFPDLDLIDAYEPSA
QTLETQARIAEEHARAVKGVTNSDGGSATWSSSRWALVTSDGFHGAHAATGHSISASAIA
GEGAGMERGGEGRSTRHFGDLPAAGDIGMEAGRQAVARLNPRKIASTTAPVIFENRLAMS
LIGPLLGAISGPSIARGTSFLKDKLGQAIFAKGVNLLEDPHRVRGLGSAPFDDEGVATQA
RALIEDGVLTTWLLNTSAAKQLGLATTGHASRGLAGPSGVSAHNLTLQPGAQDLKGLMQD
AGTGLVVTSMFGPSLNGNTGDWSVGCSGYWFENGESTGPVTEITVAGNLIDIYARLVPGS
DLEFRGASNSPSLLVDALAIAGK