Protein Info for CCNA_00254 in Caulobacter crescentus NA1000

Annotation: RarD family membrane permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 46 to 66 (21 residues), see Phobius details amino acids 78 to 98 (21 residues), see Phobius details amino acids 109 to 126 (18 residues), see Phobius details amino acids 134 to 151 (18 residues), see Phobius details amino acids 156 to 172 (17 residues), see Phobius details amino acids 184 to 202 (19 residues), see Phobius details amino acids 214 to 236 (23 residues), see Phobius details amino acids 243 to 265 (23 residues), see Phobius details amino acids 271 to 291 (21 residues), see Phobius details PF00892: EamA" amino acids 13 to 147 (135 residues), 29.5 bits, see alignment E=4.2e-11 TIGR00688: protein RarD" amino acids 20 to 263 (244 residues), 180.4 bits, see alignment E=2.2e-57

Best Hits

Swiss-Prot: 38% identical to RARD_SALTI: Protein RarD (rarD) from Salmonella typhi

KEGG orthology group: K05786, chloramphenicol-sensitive protein RarD (inferred from 100% identity to ccr:CC_0254)

Predicted SEED Role

"RarD protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C451 at UniProt or InterPro

Protein Sequence (300 amino acids)

>CCNA_00254 RarD family membrane permease (Caulobacter crescentus NA1000)
MPPHSQTESRSAYAAGVGCYLLWGFLPLYFHLLAKLGVTSWEMIAHRSLWSVLWALGLVL
IARQVGQVAQVLRQPKTLGVLALTTLAIFSNWTIYVFAVNAGHVIEASLGYYINPLMNMA
AGALLFRERMSTEGKVAIGLAAVGVAIQTVALGHLPIVSLGLALTFCVYAILRKQVKADA
QTGLFIECAYLALPGLAYVWFLQSSGQGHFGDGASVTTLLALAGPATVVPLALFAWSARR
LPLSAVGFLQFIAPTIQFLLGVAFGEPFTPLRALSFVFIWLGVATFAYGAWRKAKALSPA