Protein Info for CCNA_00185 in Caulobacter crescentus NA1000

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 841 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details PF07715: Plug" amino acids 87 to 196 (110 residues), 60.6 bits, see alignment E=2e-20 PF00593: TonB_dep_Rec" amino acids 333 to 803 (471 residues), 153.4 bits, see alignment E=1.9e-48

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_00185)

Predicted SEED Role

"Outer membrane receptor proteins, mostly Fe transport" in subsystem Hemin transport system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C662 at UniProt or InterPro

Protein Sequence (841 amino acids)

>CCNA_00185 TonB-dependent receptor (Caulobacter crescentus NA1000)
MAISSPGFLTRGLDMSFTQRNDATKALLLAALLCGGASGAYAGVTEGSTVPGAVATASES
AESDGSNVAGATVEALTITARRRSETVQSVPLAVSVVGGDRLDGTGSFNVGRLQQLTPTL
QFYSSNPRNTAVNIRGLGVPFGLTSDGFEQGVGIYVDDVYNSRVATATFDFLDVDRIEVL
RGPQGTLYGKNTTAGAINITTRQPTFDFEANAEVSLGNLDYKQAKAAISGPLSDKLAARF
AVSSTHRRGTIYNVTSRRYINEQDNLGLRGQLLFKPSEDLAVTLAADYSAQDPEGFAQIY
VRTGATQRALNRQYAALTSALGYAVPSTNAFDRVTDVDAELNAGNKVGGASAKVAWNVAG
GTLTSVTAWRFWDWKPQNDRDFLGLSIVAKSQNPSQQDQYSQELRFNRSWDSHDLVVGAF
AFHQRIDTQGTEQQGVNASRWNINPSNALSNDPTVLAGLTALNTQWLKSTSFAVFGQLSW
KVTDALTLTPGARLNYDEKSGFYERKVIDGQGVPVLLTDTGARRAAQLAVYTPQVSAPSF
DDWNFTYDLSASYQLDRDVLAYATYAKSFKTGGINQNGLPTDAAGKPIEAAGAIKPEDIN
HFEGGLKTQWLDRTLTANLAVFRSDIKNYQATVSNGQLGVLRGYLANAGKVRTQGVELDS
AYRPNARFSTYLNAAYTDAKYVRFVDAPCPPELSGGTVATGTQVPRAAGVAGALSPANCD
VSGQRLPGVSKWSVALGAEANVPGDFLGKTGEFYVGYDGSYRSKFSSNPSPSIYTWVDGY
TIANFRAGFRTPEGLNLYAWVRNAFDENYFEQLAVGPSNTGLIAGQPGDPRTWGVTLRAA
F