Protein Info for CCNA_00181 in Caulobacter crescentus NA1000

Annotation: type II secretion pathway protein M

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 158 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details PF04612: T2SSM" amino acids 6 to 155 (150 residues), 131.1 bits, see alignment E=2.2e-42

Best Hits

KEGG orthology group: K02462, general secretion pathway protein M (inferred from 100% identity to ccs:CCNA_00181)

Predicted SEED Role

"General secretion pathway protein M"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C2Y8 at UniProt or InterPro

Protein Sequence (158 amino acids)

>CCNA_00181 type II secretion pathway protein M (Caulobacter crescentus NA1000)
MNGRLEAARLWWTGRTGREQVLLAVMVAALVVVIGWYGVATPLWSAAKTAQVRVDKAATQ
LATLRGLAAGASRATAGGAAPQAVVEAAASRVGLPIARHRQDANGRFTIWIAAIDSKILL
PWTAGLEREGAVKVTDFTASRLDNGLIEAEITFARAAP