Protein Info for CCNA_00180 in Caulobacter crescentus NA1000

Annotation: type II secretion pathway protein L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 368 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 223 to 243 (21 residues), see Phobius details TIGR01709: type II secretion system protein L" amino acids 11 to 366 (356 residues), 289.5 bits, see alignment E=2.1e-90 PF05134: T2SSL" amino acids 47 to 167 (121 residues), 74 bits, see alignment E=1.2e-24 PF12693: GspL_C" amino acids 221 to 367 (147 residues), 124 bits, see alignment E=5.3e-40

Best Hits

KEGG orthology group: K02461, general secretion pathway protein L (inferred from 100% identity to ccr:CC_0181)

Predicted SEED Role

"General secretion pathway protein L"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C657 at UniProt or InterPro

Protein Sequence (368 amino acids)

>CCNA_00180 type II secretion pathway protein L (Caulobacter crescentus NA1000)
MDPRRMTLLSLLILPAAPDEPAQLLQDYGLSVTRRTLAPDERLDEVGAVILVAPGEEVVA
RWMDLPMGSAAQARSAAAFRLEDEVALGAEDLHIAVGEADAAGRTLVVWTARDKLQAWLD
MAQTHGLAPQAVIPDYLLLPEAEDGVLTVGRLGARLALREPSKALSADADLAALLFENRE
HRYLAGKELDAQLITGARAPVINLLQGRFAVRTTGGRGGLRRLAILTAAAVLSPLLLMIA
QIAHDQWTARALERQATKLAVSLAPQASRYEDAVGYALSRLAASQSGQGFGDLSASYLSM
VESTPGVTLDTLVYGEEGAIRSTIVYNNYSDMDQLRLGAKRLGLELTEQSTASEGGRISS
DLIIRRKP