Protein Info for CCNA_00143 in Caulobacter crescentus NA1000

Annotation: ribosomal RNA small subunit methyltransferase I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase" amino acids 19 to 285 (267 residues), 225.9 bits, see alignment E=3.2e-71 PF00590: TP_methylase" amino acids 19 to 219 (201 residues), 118.2 bits, see alignment E=2.6e-38

Best Hits

Swiss-Prot: 51% identical to RSMI_RHILO: Ribosomal RNA small subunit methyltransferase I (rsmI) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)

KEGG orthology group: K07056, (no description) (inferred from 100% identity to ccr:CC_0144)

Predicted SEED Role

"rRNA small subunit methyltransferase I" in subsystem Heat shock dnaK gene cluster extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C5A7 at UniProt or InterPro

Protein Sequence (290 amino acids)

>CCNA_00143 ribosomal RNA small subunit methyltransferase I (Caulobacter crescentus NA1000)
MSRLLPPPALSDAPFAPGLYLVATPIGNLRDITLRALDVLAGCDVLLAEDTRVTGKLLSA
YGIRTRLERHDEHVAERSIPGILERLAAGERVALVSDAGTPMVSDPGYRLAREAIAAGHD
VIPIPGASAALAALTLAGLPTERFLFAGFPPPKSAARRTFFEEFANTRATLIFYEGASRV
ADCLADMAAVFGADRPAAVCRELTKLYETCVRGPLSDLAADPRFDAPKGEIVILVGPGAE
KVASADDAEAALREAMARLPLGEAASEVAKALGLSRKDLYRQALALKEQA