Protein Info for CA265_RS24610 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: DNA polymerase IV

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 PF00817: IMS" amino acids 15 to 162 (148 residues), 172.3 bits, see alignment E=9.8e-55 PF11798: IMS_HHH" amino acids 174 to 205 (32 residues), 29.5 bits, see alignment (E = 8.8e-11) PF11799: IMS_C" amino acids 249 to 353 (105 residues), 94.8 bits, see alignment E=6.4e-31

Best Hits

Swiss-Prot: 58% identical to DPO4_LEPIC: DNA polymerase IV (dinB) from Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)

KEGG orthology group: K02346, DNA polymerase IV [EC: 2.7.7.7] (inferred from 66% identity to dfe:Dfer_0318)

Predicted SEED Role

"DNA polymerase IV (EC 2.7.7.7)" in subsystem DNA repair, bacterial (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZCR2 at UniProt or InterPro

Protein Sequence (366 amino acids)

>CA265_RS24610 DNA polymerase IV (Pedobacter sp. GW460-11-11-14-LB5)
MSDLTPTVLRKIIHIDMDAFYASVEQRDFPEYRGKPLVVGGKPDSRGVVSTASYEARQYG
IRSAMSSSKAYQLCPTAIFVYPRFDAYTAVSKALREIFSRYTDLIEPLSLDEAYLDVTED
KLGIGSAIDIAQSIKDAIKNELNLTASAGVSINKFVAKVASDMNKPDGLTFIGPSKIKAF
MEKLPVEKFFGVGKVTGAKMKAMQINTGADLKKLTEAQLVAQFGKSGRFYYKIVRGIDER
PVQSHRETKSVGAEDTFPEDTNEDSVMHDLLKQISETVAKRLEKYQLSGKTVTLKIKFAD
FKLITRSRSFAAPINKAEVIYAEAIKLLEEAALGTTQVRLLGITLSRFYDDVEIEKPESN
QLEFEF