Protein Info for CA265_RS21990 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: glycosyl hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 868 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00703: Glyco_hydro_2" amino acids 242 to 335 (94 residues), 50.4 bits, see alignment E=5.2e-17 PF02836: Glyco_hydro_2_C" amino acids 402 to 485 (84 residues), 21.3 bits, see alignment E=2.1e-08 PF18368: Ig_GlcNase" amino acids 757 to 860 (104 residues), 96.5 bits, see alignment E=1.5e-31

Best Hits

KEGG orthology group: None (inferred from 63% identity to cpi:Cpin_2275)

Predicted SEED Role

"Beta-mannosidase (EC 3.2.1.25)" in subsystem Mannose Metabolism (EC 3.2.1.25)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZB48 at UniProt or InterPro

Protein Sequence (868 amino acids)

>CA265_RS21990 glycosyl hydrolase (Pedobacter sp. GW460-11-11-14-LB5)
MKKIFLLFLLCSALIVDAQQRYELNSGWVCTNIKEAKANGSEISKAGFSTNNWMPATVPG
TVLTTLLNNKKVPDPFYGMNNEKIPDVYKTGNDYYTYWFVKDFEEHAVGNEQVWLQFRGI
NYKAEIYLNGKKVNPKTQVGMHLRAQYNITKLLSSNGKNRLAVIVYPPDFPGNPNGGQGG
DGTIAKGLTTQYTAGWDWIQPTRDRNTGIWDKVTIEKTKSINIQNPQVITLVPGKRLPEG
KQNPATVKVSVEVENPTGQAVSGTLQYQIAGKLIKQPATIAANKTTTVKLPDLQLENPKL
WWPSGYGPQNLYEVKIEFVAANQVLDQEQLKVGVRQIDNIWNGHTQSMGAYVNGQKIFIK
GGNWIISDAMLRFSDARYDAEVRYHKDMNLNLIRIWGGAILERPEFYNACDKYGLLIFQD
FWFSGDCNGRWVDPMKKEDQWTRRNYPDDHHLTLTAIEDQIKMIRNHASLAFWCGGNEIT
PPEDILEPLKNDILPRLDGTRKLFDFSNSDEMSFNSIGGNGDGPYGIQDIKTFWGTRTFP
YNSEVGSVGVGDYVSLLRFIPKENLIAPQYKAKPDSVWDYHKYISYEQYLNPYGKPKSAE
DFAMKAQLANYDQYRALMEGFSNKMWDWYTGSIIWKTQNPWTAMRGQMYDYYLDPNACLY
GLRKGSEPLHVMMNPLDSMVTIVNNGFTTRNNLMVQAKAYDMDGKDYFYSQVFNSVGPSS
VRRLFPMNEFLTKLDKKEGVFVSLRILDQKQNILSENIYWLPGKDGEYSGLKNIKQTPLK
VAAVNQKNGKVTVTLSNASGNPVAFFNRVALINGNSGERILPAFYDDNYVSILPGESKTV
TVEYTGKQSNLGVEVYGWNVAKQKVSIQ