Protein Info for CA265_RS21120 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: CPBP family intramembrane metalloprotease domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 20 to 45 (26 residues), see Phobius details amino acids 63 to 84 (22 residues), see Phobius details amino acids 103 to 125 (23 residues), see Phobius details amino acids 160 to 180 (21 residues), see Phobius details amino acids 202 to 222 (21 residues), see Phobius details amino acids 234 to 261 (28 residues), see Phobius details amino acids 278 to 297 (20 residues), see Phobius details PF02517: Rce1-like" amino acids 165 to 253 (89 residues), 77.5 bits, see alignment E=4e-26

Best Hits

KEGG orthology group: K07052, (no description) (inferred from 48% identity to phe:Phep_0019)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZAW4 at UniProt or InterPro

Protein Sequence (308 amino acids)

>CA265_RS21120 CPBP family intramembrane metalloprotease domain-containing protein (Pedobacter sp. GW460-11-11-14-LB5)
MNFVTPNKEEINPFLQLLLLLFYAVIGGLVFGILAIAIVLMMYGLGIVSNLDMLLAGDPK
YIGGFKVIQILSSIGTFILPPIALALTERKKVTEFYLFRQPKFLLVVLVLAIMILSMPFM
EWTVIWNQKMVLPDFLHQIEQWMKEKEAIAMKMTIQLITVRSNFDFIVNLIMIAVIPAVG
EELMFRGGVQRSLNRAFENPHVAIWLSAIIFSAIHVQFYGFVPRMLLGAGFGYLYYFSGS
IWYAMLAHFINNAYAVCAAFYMQKHHMPLDKADEPIGFPWYGYLISAIITIALFKFFKDS
ATRERKLG